2021 "Digital Source Cup" Million Single Cell Gene Expression Data Algorithm Contest

The Mammoth International Contest on Omics Science
Contest Introduction

The "Digital Source Cu" Million Single-Cell Gene Expression Data Algorithm Contest was officially opened on May 17 to encourage researchers and practitioners in related fields to develop and optimize single-cell clustering algorithms based on the millions of single-cell data resources stored in the National Gene Bank's Big Data Platform, which is an important step in single-cell data analysis. At the same time, the contest provides a platform for cross-disciplinary technical exchange among professionals in life sciences, medicine, computer science, and other fields. The contest attracted the participation of professionals and technicians from more than 100 well-known universities and nearly 90 enterprises and institutions at home and abroad, including Peking University, Tsinghua University, Boston University, Children's Hospital of Philadelphia, Institute of Computing, Chinese Academy of Sciences, Huawei, Tencent, Baidu, Ping An Technology and so on. A total of 1819 works were submitted.

The Mammoth International Contest on Omics Science
Contest Setting

"Digital Source Cup" Million Single Cell Gene Expression Data Algorithm Contest: This contest aims to improve the performance of single-cell clustering algorithms, requiring participants to develop/optimize single-cell clustering algorithms to reduce memory and increase computing speed while ensuring the accuracy of analysis results using data resources provided by the organizer.
Single-cell transcriptome sequencing (scRNA-seq) has become a core tool for identifying and characterizing cell types, states, lineages, and networks. Cell clustering is a common step in the analysis of single-cell data. The goal of clustering analysis is to retain the major sources of variation in the dataset of the cell type to be defined while trying to shield variation due to useless sources of variation (sequencing depth, cell cycle differences, mitochondrial expression, batch effects, etc.). Several well-established single-cell clustering algorithms exist, such as classical hierarchical clustering and K-means, as well as SC3 clustering developed specifically for single-cell technology. However, as single-cell data continues to be produced, the throughput of data processing will continue to climb, so the performance of single-cell clustering algorithms needs to be continuously improved.

The Mammoth International Contest on Omics Science
Format of the contest

1. Participants are required to complete the formation of teams (maximum 5 persons per team) and register and submit materials for each phase of the contest as a team. One participant is allowed to participate in only one team.
2. Teams will download the data resources from the contest platform, complete the algorithm optimization locally, and submit the work in each phase on time according to the contest schedule. The work includes analysis results, algorithm source code, and related documents (data pre-processing documents, algorithm model documents, algorithm operation (environment) documents), including team introduction materials for the preliminary round and defense materials (PPT) for the final round.
3. the contest invites a panel of experts in the field of single-cell and big data to conduct code evaluation and comprehensive evaluation of the works in each session.* Preliminary round can register, watch training videos, and interact with the expert panel online.

Awards Setting

First Prize: 1 team, RMB 20,000
Second Prize: 2 teams, RMB 10,000
Third Prize: 3 teams, RMB 3,000
Fourth prize: 4 teams, RMB 1,000

Award List
Rank Team Name Institution
First Prize How can I go without the fielding (Jiaxin Liu) Huazhong University of Science and Technology
Second Prize FakeDr (Zheng Cao) Zhejiang University
Elite Squad (Yunpei Xu) Central South University
Third Prize Drink more hot water (Jun Ren) Xiamen University
Slack Off Trio (Shengquan Chen , Yun Fang, Zhen Li) Tsinghua University
Want to have afternoon tea (Dehua Feng、Zhong Yu) Boston University, Xi'an Jiaotong University
Outstanding Award How many people can't cross the hurdle of love (Yuxuan Chen, Siqi Chen, Zhenlan Liang, Ruiqing Zheng, Xuhua Yan) Central South University
Top Understanding (Jing Hu, Zijing Liu, Yang Xue, Jun Zhu, Weijin Zou) Tongji University, Baidu China, etc.
Sildenafil (Xiaowei Tang, Linshu Wang) Peking University
Three times two minus one (Jinyi Liao, Zhiwen Huang, Nan Cheng, Shuntuo Xu) East China Normal University